1334237-71-6，AMG 416螯合剂
英文名称：Etelcalcetide hydrochloride
(6R,9R,12R,15R,18R,21R,24S,29R)-24-Acetamido-1,29-diamino-12,15,18-tris(3-carbamimidamidopropyl)-6-carbamoyl-1-imino-9,21-dimethyl-8,11,14,17,20,23-hexaoxo-26,27-dithia-2,7,10,13,16,19,22-heptaazatriacontan-30-oic acid hydrochloride (1:1)
AMG 416
velcalcetide hydrochloride
etelcalcetide hydrochloride
KAI-4169
UNII:72PT5993DU
AMG-416
中文名称：盐酸依特卡肽
CAS：1334237-71-6
分子式：C38H73N21O10S2.xClH
分子量：1084.712
***质量：1083.505737
描述：Etelcalcetide hydrochloride (AMG 416 hydrochloride) 是一种合成肽，有钙敏感受体 (CaSR) 活化剂的作用。Etelcalcetide hydrochloride 可有效降低接受血液透析的继发性甲状旁腺功能亢进患者的甲状旁腺*** (PTH) 浓度。
参考文献：
[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.
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1334237-71-6，AMG 416螯合剂